What should be administered if the INR is between 5 and 9 without major bleeding?

When the INR (International Normalized Ratio) is elevated between 5 and 9 without evidence of major bleeding, the appropriate management involves the use of vitamin K. Administering 1 to 2.5 mg of oral vitamin K is a recommended approach in such cases because it effectively helps to reverse the anticoagulation effects of warfarin without the need for more aggressive interventions.

Oral vitamin K allows the body to generate clotting factors again, thus reducing the INR to a safer level over time, which is particularly important in non-bleeding situations. This approach is preferred as it avoids the potential complications and risks associated with more invasive treatments, such as fresh frozen plasma or intravenous vitamin K, which are typically reserved for situations involving significant bleeding or higher INRs.

This method effectively addresses the increased INR while maintaining patient safety and minimizing risks associated with rapid reversals of anticoagulation.